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			<title>Help with integrating a CNN model directly into Dorado</title>
			<link>https://www.seqanswers.com/forum/sequencing-technologies-companies/oxford-nanopore/327366-help-with-integrating-a-cnn-model-directly-into-dorado</link>
			<pubDate>Wed, 17 Jun 2026 14:11:49 GMT</pubDate>
			<description>Hi everyone! 
 
I am currently working on a project  focusing on RNA modifications. I built and optimized a custom 1D-CNN ensemble architecture in...</description>
			<content:encoded><![CDATA[Hi everyone!<br />
<br />
I am currently working on a project  focusing on RNA modifications. I built and optimized a custom 1D-CNN ensemble architecture in PyTorch. <br />
However, in the lab we hit a technical roadblock while trying to deploy our trained weights into <b>Dorado</b> via ONNX for real-time basecalling. During the compilation/serialization stage, Dorado throws this error:<br />
It looks like the Dorado framework expects a very specific model signature signature/dimension structure [28] and requires an official digital signature validation core (ON_SVC) to parse custom graphs.<br />
<br />
Has anyone here successfully integrated a custom neural network model directly into Dorado? Is there a known protocol, workaround, or a specific script to sign and format the weights so the Dorado compiler accepts them?<br />
<br />
We would highly appreciate any tips, workarounds, or documentation from anyone who has managed to bypass this restriction!<br />
<br />
Thank you so much! <br />
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			<category domain="https://www.seqanswers.com/forum/sequencing-technologies-companies/oxford-nanopore">Oxford Nanopore</category>
			<dc:creator>Bioinformatics911</dc:creator>
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