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CRISPR-Associate (Cas) protein is a kind of RNA-mediated double-stranded DNA endonuclease which own the ability to cleave exogenous DNA. When the conserved spacer proto-adjacent motif (PAM) is present in the invading DNA sequence, the target DNA sequence will be cleaved in the spacer sequence upstream (4-5nt) of the PAM. So what about the applications of CRISPR Based Microbe Genome Editing Service.
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The introduction of single-cell sequencing has advanced the ability to study cell-to-cell heterogeneity. Its use has improved our understanding of somatic mutations1, cell lineages2, cellular diversity and regulation3, and development in multicellular organisms4. Single-cell sequencing encompasses hundreds of techniques with different approaches to studying the genomes, transcriptomes, epigenomes, and other omics of individual cells. The analysis of single-cell sequencing data i
...01-24-2023, 01:19 PM -
Single-cell sequencing is a technique used to investigate the genome, transcriptome, epigenome, and other omics of individual cells using high-throughput sequencing. This technology has provided many scientific breakthroughs and continues to be applied across many fields, including microbiology, oncology, immunology, neurobiology, precision medicine, and stem cell research.
The advancement of single-cell sequencing began in 2009 when Tang et al. investigated the single-cell transcriptomes...01-09-2023, 03:10 PM