I've jsut stated using the Covaris for chromatin fragmentation and so far I'm very impressed with the results. The reproducibility between samples is impressive.
What I am wondering is what are the advantages/disavantages of using the Covaris vs. chemical methods for shearing RNA for RNA-seq library preparation?
What I am wondering is what are the advantages/disavantages of using the Covaris vs. chemical methods for shearing RNA for RNA-seq library preparation?
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