Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • CNVnator: The format of cnv result

    I know CNVnator has been used in 1000 Genomes Project. But there is little of material to explain the format of CNV result. Is there anyone know the format of cnv result? For example:
    deletion chr10:6070441-6074520 4080 0.674906 0.00834134 72162.3
    It is very easy to understand the first three column mean, but is there any can explain the rest of column mean?

  • #2
    This is what I got from the author of CNVnator:

    CNV_type coordinates CNV_size normalized_RD p-val1 p-val2

    normalized_RD -- normalized to 1.
    p-val1 -- is calculated using t-test statistics.
    p-val2 -- is from probability of RD values within the region to be in
    the tails of gaussian distribution describing frequencies of RD values in bins.

    Comment


    • #3
      Thx bioworker,
      I think it will help me a lot.

      Comment


      • #4
        Do the graphs make any sense? It would be great if any of you can explain it to me.

        I graphed the below region and here is what I get:
        Code:
        duplication chr1:172376901-172381900	5000	10.2	2.54996e-10	2.65008e-29

        Comment


        • #5
          So is there any rules should be used to filter the results based on p-val1 or p-val2? Or all the output on screen are candicate?

          Comment


          • #6
            same question: how to filter result, and which p-val should be considered?

            Comment


            • #7
              same doubt - how to filter the CNVs.
              Maybe p-value of <0.01 or <0.05
              And about the size of CNVs?

              Comment

              Latest Articles

              Collapse

              • seqadmin
                Advanced Methods for the Detection of Infectious Disease
                by seqadmin




                The recent pandemic caused worldwide health, economic, and social disruptions with its reverberations still felt today. A key takeaway from this event is the need for accurate and accessible tools for detecting and tracking infectious diseases. Timely identification is essential for early intervention, managing outbreaks, and preventing their spread. This article reviews several valuable tools employed in the detection and surveillance of infectious diseases.
                ...
                Yesterday, 01:15 PM
              • seqadmin
                Strategies for Investigating the Microbiome
                by seqadmin




                Microbiome research has led to the discovery of important connections to human and environmental health. Sequencing has become a core investigational tool in microbiome research, a subject that we covered during a recent webinar. Our expert speakers shared a number of advancements including improved experimental workflows, research involving transmission dynamics, and invaluable analysis resources. This article recaps their informative presentations, offering insights...
                11-09-2023, 07:02 AM

              ad_right_rmr

              Collapse

              News

              Collapse

              Topics Statistics Last Post
              Started by seqadmin, Yesterday, 08:12 AM
              0 responses
              14 views
              0 likes
              Last Post seqadmin  
              Started by seqadmin, 11-22-2023, 09:29 AM
              1 response
              46 views
              0 likes
              Last Post VilliamPast  
              Started by seqadmin, 11-22-2023, 08:53 AM
              0 responses
              30 views
              0 likes
              Last Post seqadmin  
              Started by seqadmin, 11-21-2023, 08:24 AM
              0 responses
              23 views
              0 likes
              Last Post seqadmin  
              Working...
              X