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But doesn't VCF always show forward strand??
It is a G only if it is in the reverse strand. And the base before the event is a C in the forward strand, right?Leave a comment:
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According to the website it's a G: http://www.ncbi.nlm.nih.gov/projects...gi?rs=67024588, so it depends on what strand you are annotating with.Leave a comment:
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I am fixing this by hand now. How should I fix rs67024588? Are the alleles also wrong because at chr19:52004794 is C?
19 52004794 rs67024588 C CC . PASS GENEINFO=SIGLEC12:89858;GNO;RSPOS=52004794;RV;S3D;SAO=0;SLO;SSR=0;VC=DIV;VP=050300000000000100000200;WGT=0;dbSNPBuildID=130
Is this ok???Leave a comment:
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Oh I see. I think I will just fix that file with RSPOS positions. Thanks for your reply.Leave a comment:
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I found something that I think was similar and concluded was a bug months ago; I emailed them and one of them acknowledged it was a bug. I check back with them a few weeks later and I was told that he passed the information on to the relevant person and I haven't heard back. This was at least a few months ago.
It may have been completely different then what you just posted but my conclusion is that I would not be surprised if there are numerous errors where things are off by 1 bp or maybe a couple more for indels.Leave a comment:
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Genomic Positions off in db135.b37.vcf
I noticed some indels in db135.b37.vcf I downloaded from
ftp://[email protected]
For example:
19 51835892 rs11402251 T TG . PASS GENEINFO=VSIG10L:147645;GNO;RSPOS=51835893;SAO=0;SLO;SSR=0;VC=DIV;VP=050100000000000100000200;WGT=0;dbSNPBuildID=120
19 52004791 rs67024588 G GC . PASS GENEINFO=SIGLEC12:89858;GNO;RSPOS=52004794;RV;S3D;SAO=0;SLO;SSR=0;VC=DIV;VP=050300000000000100000200;WGT=0;dbSNPBuildID=130
But we can see that the correct position is in "RSPOS=" but the second field is off.
Is this a bug or a feature???
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