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  • BWA Compression

    Hi everybody,
    I would like to save each aligned reads in my database using the Bam compression scheme. Does anyone can give me some reference where I can find how exactly bam compression works? Thanks in advance

  • #2
    For starters you can have a look at the end of the SAM specification: samtools.sourceforge.net/SAM1.pdf

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    • #3
      The short answer is BAM is a binary version of SAM, and is compressed using a variation of the general purpose compression library/format GZIP.

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