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  • jujubix
    replied
    Are you considering the possibility of differences in transcript modification? (i.e. RNA editing) These could explain changes in the protein without any changes in the genome that you're seeing.

    Leave a comment:


  • biocc
    started a topic how to explain SNPs and proteomics data

    how to explain SNPs and proteomics data

    Hi everyone,
    We did comparative proteomics between a mutant and wide type strain. For understanding the reason of changes at the protein level, we re-sequenced the mutant strain. we detected some SNPs, but almost no SNP located CDS whose protein has changes in proteomics data. What I mean is the relation between SNPs and Proteomics data could not be found by direct analyses. Then what should I do?
    please give me some suggestion. Thanks

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