Mauve Alignment Viewer: similarity profile
Hi,
I hope this is not too obvious a question, but so far I was just not able to solve it myself:
In the Mauve Alignment Viewer, one sees these colored blocks and inside each block, Mauve draws a similarity profile of the genome sequence.
I don't understand what this similarity profile actually shows: I have a reference genome, and one genome aligned to it. Why is there a similarity profile shown for both genomes (is the similarity shown of genome 1 to 2 and vice versa?), and more importantly, why do they look DIFFERENT in homolog blocks? Shouldn't they be exactly equal in homologs?
Any help with this is greatly appreciated!
Hi,
I hope this is not too obvious a question, but so far I was just not able to solve it myself:
In the Mauve Alignment Viewer, one sees these colored blocks and inside each block, Mauve draws a similarity profile of the genome sequence.
I don't understand what this similarity profile actually shows: I have a reference genome, and one genome aligned to it. Why is there a similarity profile shown for both genomes (is the similarity shown of genome 1 to 2 and vice versa?), and more importantly, why do they look DIFFERENT in homolog blocks? Shouldn't they be exactly equal in homologs?
Any help with this is greatly appreciated!
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