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What is the mutation detection rate for 454, solexa, and SOLiD if any one have any idea, is there any pub referenced on that ? Thanks
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There was a paper involving P. stiptis which indicated that all three platforms were able to pick up known SNPs with only a very small false discovery rate and a zero false negative rate. Basically on this small organism and at a high depth of coverage all three platforms work equally well. At least that is what I remember. I don't have the citation off hand so that the above with a grain of salt.
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Innovations in next-generation sequencing technologies and techniques are driving more precise and comprehensive exploration of complex biological systems. Current advancements include improved accessibility for long-read sequencing and significant progress in single-cell and 3D genomics. This article explores some of the most impactful developments in the field over the past year.
Long-Read Sequencing
Long-read sequencing has seen remarkable advancements,...12-02-2024, 01:49 PM
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