I can not figure out why I am getting the message, 'TopHat did not find any junctions in GTF file',
as well as the error, 'Couldn't build bowtie index with err = 1'.
When this file, TAIR10_GFF3_genes.gff, is used, eveything works fine.
However, when this file, ath_miRBase_miRNA_Cap-Chr_V.gff3, is used, the error appears.
The command line is (the only difference being the file after the -G switch).
./tophat --library-type fr-unstranded
-o /A_ATCACG_set1_mRNA_TH-out
-G /ath_miRBase_miRNA_Cap-Chr_V.gff
/TAIR10_C_Bt2
/A_ATCACG_L008_R1.fastq
I have used bowtie2-inspect -n, and made sure the names are the same in the genome index, TAIR10_C_Bt2, and the gff3 file.
The formatting of the two gff files (the one that does work and the one that doesn't) seems exactly the same to me.
as well as the error, 'Couldn't build bowtie index with err = 1'.
When this file, TAIR10_GFF3_genes.gff, is used, eveything works fine.
HTML Code:
Chr1 TAIR10 chromosome 1 30427671 . . . ID=Chr1;Name=Chr1 Chr1 TAIR10 gene 3631 5899 . + . ID=AT1G01010;Note=protein_coding_gene;Name=AT1G01010 Chr1 TAIR10 mRNA 3631 5899 . + . ID=AT1G01010.1;Parent=AT1G01010;Name=AT1G01010.1;Index=1 Chr1 TAIR10 protein 3760 5630 . + . ID=AT1G01010.1-Protein;Name=AT1G01010.1;Derives_from=AT1G01010.1 Chr1 TAIR10 exon 3631 3913 . + . Parent=AT1G01010.1
HTML Code:
Chr1 TAIR10 chromosome 1 30427671 . . . ID=Chr1;Name=Chr1 Chr1 TAIR10 miRNA_primary_transcript 28500 28706 . + . ID=MI0005394_1;accession_number=MI0005394;Name=ath-MIR838 Chr1 TAIR10 miRNA 28635 28655 . + . ID=MIMAT0004260_1;accession_number=MIMAT0004260;Name=ath-miR838;derives_from=MI0005394_1 Chr1 TAIR10 miRNA_primary_transcript 78927 79037 . - . ID=MI0000199_1;accession_number=MI0000199;Name=ath-MIR165a
./tophat --library-type fr-unstranded
-o /A_ATCACG_set1_mRNA_TH-out
-G /ath_miRBase_miRNA_Cap-Chr_V.gff
/TAIR10_C_Bt2
/A_ATCACG_L008_R1.fastq
I have used bowtie2-inspect -n, and made sure the names are the same in the genome index, TAIR10_C_Bt2, and the gff3 file.
The formatting of the two gff files (the one that does work and the one that doesn't) seems exactly the same to me.