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  • crazyhottommy
    replied
    what do you mean by "know transcription factor binding sites"?
    if you mean the binding sites determined by ChIP-seq experimentally, I think you have to download the corresponding ChIP-seq data for corresponding TFs, peak call to generate a bed file, and just do a overlap with your DMRs to see any of them overlap.

    you can do it through Galaxy or you can use bedtools.

    Leave a comment:


  • Chrevan
    replied
    You can try Homer, a tool for ChIP-Seq analysis, including Motif analysis, known motifs will be found.

    Leave a comment:


  • Searching known TF binding sites for matching motif?

    Hi,

    I have a list of DMRs that I have sent through MEME to identify common motifs. I would like to search known transcription factor binding sites for these motifs to see whether any of them correspond. Is there a tool that can do this? This is for humans.

    Thanks!

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