a new paper, by analyzing millions of RNA-binding protein (RBP) binding sites from 117 CLIP-Seq datasets generated by 50 independent studies, we identified 22,735 RBP–lncRNA regulatory relationships.
RBP–lncRNA interactions were available at http://starbase.sysu.edu.cn/rbpLncRNA.php.
an invited paper described these protein–lncRNA interactions has been published in Frontiers journal.
The genome-wide binding map of Ezh2 in mouse.
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Originally posted by zhxq09 View Postregarding circRNABase in Starbase I'd like to know:
a) in search page, which input in the field circRNA Symbol has to be inserted?
b) When I select a specific miRNA(hsa-let-7a-5p) the output target is RRP1B_hsa_circ_001854,what does the name before the circRNA name (e.g. RRP1B) mean?
We did not displayed circRNAs without miRNA target sites supported by CLIP-Seq.
RRP1B is the gene symbol that were fetched from circBase (http://circbase.org/cgi-bin/downloads.cgi). This means that the circRNA is originated from the gene in circBase.
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regarding circRNABase in Starbase I'd like to know:
a) in search page, which input in the field circRNA Symbol has to be inserted?
b) When I select a specific miRNA(hsa-let-7a-5p) the output target is RRP1B_hsa_circ_001854,what does the name before the circRNA name (e.g. RRP1B) mean?
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Originally posted by zhxq09 View PostHow can i find the lncRNAs with chromosome locations but not gene names in starBase?
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How can i find the lncRNAs with chromosome locations but not gene names in starBase?
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Originally posted by zhxq09 View Postin starBase download page, what a numerical value (displayed in the score column of bed files) means? Is it CLIP-Seq peak height? It can be further used to filter Protein-RNA interactions?
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in starBase download page, what a numerical value (displayed in the score column of bed files) means? Is it CLIP-Seq peak height? It can be further used to filter Protein-RNA interactions?
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Originally posted by zhxq09 View PostHow can I download Pan-Cancer data (14 cancer types) of miRNA-lncRNA, protein-lncRNA, competing endogenous RNA (ceRNA) pairs from your website.
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How can I download Pan-Cancer data (14 cancer types) of miRNA-lncRNA, protein-lncRNA, competing endogenous RNA (ceRNA) pairs from your website.
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Originally posted by rnaNGS View PostYes, you are right. We just only identified a little of lncRNAs (filtered by CPC software and other softwares) from TCGA level 3 datasets. TCGA level 3 data almost all are protein-coding genes.
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Originally posted by xiaomagege View Post
As I know, TCGA dose not provide lncRNA annotation on level 3 dataset. How many lncRNA records have you identified? Thank you~Last edited by rnaNGS; 03-19-2014, 11:10 PM.
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How to identify lncRNA genes from TCGA level 3 dataset.
As I know, TCGA dose not provide lncRNA annotation on level 3 dataset. How many lncRNA records have you identified? Thank you~
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Pan-Cancer lncRNA, RNA-RNA and Protein-RNA networks from TCGA 14 cancer types
We're pleased to announce the release of the Pan-Cancer Analysis Platform on the starBase by mining expression profiles(RNA-Seq, miRNA-Seq) of lncRNAs, miRNAs, and mRNAs across 14 cancer types (>6000 samples) from The Cancer Genome Atlas (TCGA) Data Portal(all data available without limitations).
We hope this platform will greatly help biologists to explore the impact of lncRNA, miRNA, mRNA, RNA-Binding Protein (RBP) genes and their regulatory networks (ceRNA, co-expression etc.) on human cancers and other diseases.
We are looking forward to hearing your feedback!
Overview:
Cancer types as follows:
Urothelial bladder cancer (BLCA)
Breast cancer (BRCA)
Colon and Rectal adenocarcinoma (CRC)
Glioblastoma multiforme (GBM)
Head and neck squamous cell carcinoma (HNSC)
Chromophobe renal cell carcinoma (KICH)
Clear cell kidney carcinoma (KIRC)
Acute Myeloid Leukemia (LAML)
Lung adenocarcinoma (LUAD)
Lung squamous cell carcinoma (LUSC)
Ovarian serous cystadenocarcinoma (OV)
Cutaneous melanoma (SKCM)
Papillary thyroid carcinoma (THCA)
Uterine corpus endometrial carcinoma (UCEC)Last edited by yjhua2110; 07-25-2014, 05:22 AM.Tags: None
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