I am working on whole exome data. i have 7 samples but no matching normal sample. i am to detect SV/CNV variant for these samples.
The sequencing platform is Illumina and i have BAM files ready for variant calling.
Are the tools PINDEL , BREAKSEQ and CNVnator Appropriate for Whole Exome Sequencing data without matching normal sample? i have tried ready the tool publication but they only refer to NGS data, not Exome Data Compatibility in Specific. If possible are any other tools available for WES Data without matching Normal!
NEED HELP!!!!!!!
The sequencing platform is Illumina and i have BAM files ready for variant calling.
Are the tools PINDEL , BREAKSEQ and CNVnator Appropriate for Whole Exome Sequencing data without matching normal sample? i have tried ready the tool publication but they only refer to NGS data, not Exome Data Compatibility in Specific. If possible are any other tools available for WES Data without matching Normal!
NEED HELP!!!!!!!
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