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  • a_mt
    started a topic mutSig on target capture data

    mutSig on target capture data

    Hi all,

    As the title goes, can we use MutSig on the data obtained from targetted capture sequencing of around 500 genes to detect significantly affected genes ?

    My guess is because of Background Mutation Rate model of MutSig, it may not work properly on targetted capture data. Can anyone suggest me on this ?

    Thank you.

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  • seqadmin
    Current Approaches to Protein Sequencing
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    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM

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