Hi:
in TCGA breast data, I found using expression of genes of interest in the lab, ~120 samples segregate into two groups that have high and low expression of my gene.
I want to summarize that group 1 has higher mutation rate compared to 2nd group. Also I want to summarize the copy number alteration for both groups.
How can I get the summarized value for each groups (perhaps a mean value).
Can I use "mutation count" and 'CNA' columns from Cbioportal clinical sheets.
or Do I have to calculate that per KB of the genome how many mutations are observed?
Appreciate your help.
Thanks
Adrian
in TCGA breast data, I found using expression of genes of interest in the lab, ~120 samples segregate into two groups that have high and low expression of my gene.
I want to summarize that group 1 has higher mutation rate compared to 2nd group. Also I want to summarize the copy number alteration for both groups.
How can I get the summarized value for each groups (perhaps a mean value).
Can I use "mutation count" and 'CNA' columns from Cbioportal clinical sheets.
or Do I have to calculate that per KB of the genome how many mutations are observed?
Appreciate your help.
Thanks
Adrian