Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • Melissa
    replied
    To find overlapping variants between two files, you can use bcftools. If you want to generate a simple venn diagram, you can provide lists to http://bioinformatics.psb.ugent.be/webtools/Venn

    Leave a comment:


  • an_na
    started a topic filtering variants with R

    filtering variants with R

    Hi,

    I'm learning data analysis with R, using RStudio.
    I have my data in one file. I have variants from 3 tissue types, from 130 individuals. I would like to filter the variants within each individual, so that I can get: 1. unique variants for all 3 tissues, 2. variants common to all tissues, 3. variants common between 2 tissue types.
    The file that I'm working on has 118 columns (vcf annotated file), I would like to keep all columns.
    I've tried VennDiagram package, but it filters out variants that are present in any other individual, so in the overlapping files I loose some variants.
    I understand that I would need to use loop filtering, so that 1. I pick individuals by "ID" column, then sort variants by "variant" column and compare them between "tissue" column to output into all filtered types of variants (unique and common).

    Does anyone know how to do that???

    Cheers,
    A.

Latest Articles

Collapse

  • seqadmin
    Essential Discoveries and Tools in Epitranscriptomics
    by seqadmin




    The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...
    04-22-2024, 07:01 AM
  • seqadmin
    Current Approaches to Protein Sequencing
    by seqadmin


    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by seqadmin, Yesterday, 08:47 AM
0 responses
16 views
0 likes
Last Post seqadmin  
Started by seqadmin, 04-11-2024, 12:08 PM
0 responses
60 views
0 likes
Last Post seqadmin  
Started by seqadmin, 04-10-2024, 10:19 PM
0 responses
60 views
0 likes
Last Post seqadmin  
Started by seqadmin, 04-10-2024, 09:21 AM
0 responses
54 views
0 likes
Last Post seqadmin  
Working...
X