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  • Whole Exome analysis on a 1500 € standard PC, is that possible?

    Whole-Exome Analysis on a Mainstream Desktop PC
    We are regularly asked what kind of computer is needed to analyze Whole Exome data. We have tested it for you!



    Analysing NGS data usually is the domain of power compute servers or High-Performance Clusters, as it typically has massive volume and requires a lot of data crunching. However, the power of available CPUs is increasing, and now there are faster processors with more cores available on the market at competitive prices. This applies not only to the sector of the server “workhorses” but also to the sector of “standard” Desktop PCs. This sector is characterized by commodity hardware that is produced in high volumes and can be bought at affordable prices. While this kind of PC used to have just a single core, it is today possible to buy Desktop CPUs with as many as 16 cores.

    Given the price premium that is necessary to enter the high-performance server sector, the question arises: why not use commodity hardware for NGS data analysis? So we started an experiment: how feasible is it to do a resource-intensive whole-exome sequencing (WES) analysis on a modern Desktop PC.

    read more
    ecSeq Bioinformatics is Europe’s leading provider of hands-on bioinformatics workshops and professional data analysis in the field of Next-Generation Sequencing (NGS).

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  • seqadmin
    Strategies for Sequencing Challenging Samples
    by seqadmin


    Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...
    03-22-2024, 06:39 AM
  • seqadmin
    Techniques and Challenges in Conservation Genomics
    by seqadmin



    The field of conservation genomics centers on applying genomics technologies in support of conservation efforts and the preservation of biodiversity. This article features interviews with two researchers who showcase their innovative work and highlight the current state and future of conservation genomics.

    Avian Conservation
    Matthew DeSaix, a recent doctoral graduate from Kristen Ruegg’s lab at The University of Colorado, shared that most of his research...
    03-08-2024, 10:41 AM

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