Originally posted by pengchy
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The p-value isn't being caused by gene length, rather longer genes will tend to have more reads, meaning that there can be more evidence for or against differential expression. Other factors affecting that are within-group variability, between-group variability (i.e., fold change) and general level of expression (depending on exactly how the statistics are done). The p-value, then, is just one factor that should affect their decision of which follow-up experiment(s) to perform.
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