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Mauve 'std::ios_base::failure'

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  • Mauve 'std::ios_base::failure'

    I'm using a linux server to run progressiveMauve to align 2 genomes of the same species for synteny analysis. But I kept encounter this issue:

    $ progressiveMauve --output=output.xmfa EtH_Genome.fasta NSN_Genome.fasta
    Storing raw sequence at /tmp/rawseq452439.000
    Sequence loaded successfully.
    EtH_Genome.fasta 51859607 base pairs.
    Storing raw sequence at /tmp/rawseq452439.001
    Sequence loaded successfully.
    NSN_Genome.fasta 128363032 base pairs.
    Using weight 19 mers for initial seeds
    Creating sorted mer list
    Error creating sorted mer list
    terminate called after throwing an instance of 'std::ios_base::failure'
    what(): failed getting file size: Value too large for defined data type

    Does anyone know how can I resolve this issue? Do I have to compress my fasta file before running it?