We sequenced the diploid genome of a single individual and their transcritome.
(Poplar)
Fisrt, we identiy all the heterozygosity SNPs (genome).
If i know it's a heterozygosity SNPs, Should I do a chi square test using the number (65,89,38,28) or do a bionomal test (50,50,38,28) ?
an example of heterozygosity SNP (The numbers are counts of the two alleles observed in gDNA or cDNA)
gDNA cDNA
A 65 38
G 89 28
-
The human gut contains trillions of microorganisms that impact digestion, immune functions, and overall health1. Despite major breakthroughs, we’re only beginning to understand the full extent of the microbiome’s influence on health and disease. Advances in next-generation sequencing and spatial biology have opened new windows into this complex environment, yet many questions remain. This article highlights two recent studies exploring how diet influences microbial...02-24-2025, 06:31 AM