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That is such a thoughtful offer BillShannon, I am sure that it has helped many scientists. -
Moving metagenomics from lab to clinic
I have been working on microbiome research at Washington University in St Louis for the last 2-3 years and wanted to introduce myself. My lab has released microbiome power/sample size calculations and tests of hypotheses open source software developed for translational clinical microbiome research.
Our paper describing it provides a link to software that a statistician in your lab could use free of charge. This paper is at:
You (or your colleagues doing microbiome research) are more than welcome to use this software on your own to develop microbiome protocols and run statistical analyses. We think this software will be very important for translational clinical use of microbiome technology.
We have a second paper that analyzes taxonomies through the analysis of taxonomic trees. This paper (and a link to software) can be found at
We are currently extending this second paper to define microbiome cores and identify subgroups of samples with distinct microbiome cores using statistical criteria.
If the software seems useful and you need technical help running the software for power/sample size calculations or for designing a study, performing data analysis, writing a statistical analysis section for a grant, or other statistical help, we can discuss our helping you. Feel free to call anytime (1-314-704-8725). If I am busy I will call you back as soon as possible.
Bill Shannon
Washington Univ. in St Louis
BioRankings LLC
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