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You might want to look at ANNOVAR (command line tool) or SeattleSeq (web tool). Both of those should do what you are looking for.
JustinLeave a comment:
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Finding amino acid from a position in the human genome
To all,
I have a database of SNPs and with the chromosome and location in the human genome.
For example, in human genome GRCh37/hg19, on Chromosome 1, position 1118275, in gene TTLL10, the nucleotide is a "C" (cytosine).
If I mutate that C to a T (thymine), what amino acid would change in the TTLL10 gene?
I have 33,162 of these SNPs, so I cant do this one at a time.
Thanks in advance.
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Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...04-04-2024, 04:25 PM -
Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...03-22-2024, 06:39 AM
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