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  • Job - Senior Software Developer / Bioinformatician (Genome Annotation and Analysis)

    Applications are invited for a Senior Software Developer/Bioinformatician to join the Core Bioinformatics Group at the Earlham Institute (EI), based in Norwich, UK.

    see https://www.earlham.ac.uk/senior-sof...n-and-analysis for full job posting

    This post will focus on developing novel computational tools and pipelines for large scale annotation of genes and other genomic features across a diverse range of species including plants, mammals, fish and protists.

    This role will have responsibility for leading the development of EI's genome annotation pipelines and supporting large scale annotation / analysis projects. A key focus will be continuing the development of REAT - EI's Robust and Extendable eukaryotic Annotation Toolkit (https://github.com/EI-CoreBioinformatics/reat), building new workflows to address specific challenges relevant to the annotation of protist and plant genomes including annotation of non-culturable protists using single cell data.

    The role will develop scalable and robust methods to annotate eukaryotic species with large, repeat rich and polyploid genomes, utilising data from cutting edge sequencing technologies including PacBio IsoSeq and Nanopore.

Latest Articles

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  • seqadmin
    Current Approaches to Protein Sequencing
    by seqadmin


    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM
  • seqadmin
    Strategies for Sequencing Challenging Samples
    by seqadmin


    Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...
    03-22-2024, 06:39 AM

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