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De novo Assembly of a 40 Mb Eukaryotic Genome from Short Sequence Reads

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  • De novo Assembly of a 40 Mb Eukaryotic Genome from Short Sequence Reads

    Link: http://www.plosgenetics.org/article/...l.pgen.1000891

    De novo Assembly of a 40 Mb Eukaryotic Genome from Short Sequence Reads: Sordaria macrospora, a Model Organism for Fungal Morphogenesis

    Used Velvet to assemble from mostly Illumina Solexa data plus a bit of 454 to strengthen contig evidence and a tiny bit of Sanger sequencing. However, they claim very similar results possible without the Sanger data.
    Mendelian Disorder: A blogshare of random useful information for general public consumption. [Blog]
    Breakway: A Program to Identify Structural Variations in Genomic Data [Website] [Forum Post]
    Projects: U87MG whole genome sequence [Website] [Paper]

  • #2
    great work, personal genome sequencing is coming.

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