Сollapse of Helicos

[Apollo704]

Helicos also had a 50 lane set up, and finding enough samples to fill that much capacity is daunting. That and there's only so much you can do with ~20 base reads (again, the application problem).

I agree with MJC that it's way to early to rule out PacBio.

[Elcannibal]

Officially bankrupt and dead. RIP.

[krobison]

Officially bankrupt and dead. RIP.

Note that it is a Chapter 11 bankruptcy & they claim to be debtors-in-possession, so a total liquidation is not (yet) in the works.

[flxlex]

http://www.genengnews.com/gen-news-h...r-11/81247649/

[ftr712]

FYI, Helicos BioSciences' assets and rights were purchased by SeqLL, LLC not too long ago. I know that SeqLL is currently offering RNA and DNA sequencing services. Here's their website with the rest of the details www.seqll.com

[richieadam]

I think it's wrong to count out PacBio, especially as a technology.

The phasing info alone that can potentially be gained using a PacBio is worth quite a bit.

There is also the potential for direct observation of modified nucleotides using the kinetics data,

something that I'm interested to see pan out.

I would not be surprised to see many larger genome centers pick up a PacBio device for the sole purpose of providing scaffolding data to work hand-in-hand with their short read data.

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