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  • #16
    Helicos also had a 50 lane set up, and finding enough samples to fill that much capacity is daunting. That and there's only so much you can do with ~20 base reads (again, the application problem).

    I agree with MJC that it's way to early to rule out PacBio.

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    • #17
      Officially bankrupt and dead. RIP.

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      • #18
        Originally posted by Elcannibal View Post
        Officially bankrupt and dead. RIP.
        Note that it is a Chapter 11 bankruptcy & they claim to be debtors-in-possession, so a total liquidation is not (yet) in the works.

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        • #19
          http://www.genengnews.com/gen-news-h...r-11/81247649/

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          • #20
            FYI, Helicos BioSciences' assets and rights were purchased by SeqLL, LLC not too long ago. I know that SeqLL is currently offering RNA and DNA sequencing services. Here's their website with the rest of the details www.seqll.com

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            • #21
              I think it's wrong to count out PacBio, especially as a technology.

              The phasing info alone that can potentially be gained using a PacBio is worth quite a bit.

              There is also the potential for direct observation of modified nucleotides using the kinetics data,

              something that I'm interested to see pan out.

              I would not be surprised to see many larger genome centers pick up a PacBio device for the sole purpose of providing scaffolding data to work hand-in-hand with their short read data.
              Ornament Central

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