Tweet
It weighs a ton and takes up half a room. Why? Any engineers here that knows what's going on inside?
-
-
among other things, laser & optics, filter, cooling for the reagents and the entire interior, a liquid handling robot, an overengineered air table that runs on nitrogen - which was not really needed. -
"..an overengineered air table that runs on nitrogen - which was not really needed" please elaborate
I look at the RSII and a ONT minion and they (skipping some details) pretty much do the same thing (produce long reads). Yet the one requires concrete reinforced floors and the other can be held in your hand. Just find it astounding the difference in scale.Comment
-
One of them is an optical platform doing laser based detection of nanometre scale wells, and the other ... isn't. You can't 'skip the details' here, the details are the reasonOriginally posted by BioinformaticsBro View Post"..an overengineered air table that runs on nitrogen - which was not really needed" please elaborate
I look at the RSII and a ONT minion and they (skipping some details) pretty much do the same thing (produce long reads). Yet the one requires concrete reinforced floors and the other can be held in your hand. Just find it astounding the difference in scale.
Comment
-
PacBio captures videos from single fluorescent molecules that are in a specific location only for milliseconds. Thus, they are trying to avoid any vibrations.Comment
-
The introduction of single-cell sequencing has advanced the ability to study cell-to-cell heterogeneity. Its use has improved our understanding of somatic mutations1, cell lineages2, cellular diversity and regulation3, and development in multicellular organisms4. Single-cell sequencing encompasses hundreds of techniques with different approaches to studying the genomes, transcriptomes, epigenomes, and other omics of individual cells. The analysis of single-cell sequencing data i
...01-24-2023, 01:19 PM -
Single-cell sequencing is a technique used to investigate the genome, transcriptome, epigenome, and other omics of individual cells using high-throughput sequencing. This technology has provided many scientific breakthroughs and continues to be applied across many fields, including microbiology, oncology, immunology, neurobiology, precision medicine, and stem cell research.
The advancement of single-cell sequencing began in 2009 when Tang et al. investigated the single-cell transcriptomes...01-09-2023, 03:10 PM
Comment