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DNA Electronics partners with Roche to develop semiconductor based sequencing system
DNA Electronics, a fabless semiconductor provider of solutions for real-time DNA and RNA analysis, announced today that it has entered a partnership with 454 Life Sciences, a Roche Company. The collaboration will focus on the development of a low-cost, high-throughput, long read, high density DNA sequencing system. As part of the agreement, DNA Electronics has signed a non-exclusive licence to provide relevant IP from its proprietary semiconductor technology portfolio to Roche. This technology which enables sensitive detection of nucleotide incorporation during sequencing will build on 454 Life Sciences’ current pyrosequencing-based platform. The collaboration leverages DNA Electronics’ unique knowledge of semiconductor design and expertise in pH-mediated detection of nucleotide insertions with 454 Life Sciences’ long read sequencing chemistry to produce a seamless evolution from optical detection to low-cost, highly scalable electrochemical detection.
pdf of press release: http://www.dnae.co.uk/images/2010-11...%20License.pdf -
And it will be called "Ion Current"?...Comment
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This was pretty interesting to me also...especially since DNA Electronics licensed their tech to Ion Torrent as well.
Maybe we're heading for a big IP battle! Exciting...Comment
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Exciting indeed eco
I think the next 2 years is going to be great viewing for the impartial observer - and this site will probably give a pretty good front row seat!Comment
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Sample prep for ISFETs
I wonder if emPCR IP for sample prep will also fall into the fray. All the ISFET sensor tech will need a bead in a well for measurement until solid state nanopores come along.Comment
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Amplicon sequencing is a targeted approach that allows researchers to investigate specific regions of the genome. This technique is routinely used in applications such as variant identification, clinical research, and infectious disease surveillance. The amplicon sequencing process begins by designing primers that flank the regions of interest. The DNA sequences are then amplified through PCR (typically multiplex PCR) to produce amplicons complementary to the targets. RNA targets...03-21-2023, 01:49 PM -
Targeted sequencing is an effective way to sequence and analyze specific genomic regions of interest. This method enables researchers to focus their efforts on their desired targets, as opposed to other methods like whole genome sequencing that involve the sequencing of total DNA. Utilizing targeted sequencing is an attractive option for many researchers because it is often faster, more cost-effective, and only generates applicable data. While there are many approaches...03-10-2023, 05:31 AM
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