Hello, i am stuck on this topic: Several single nucleotide polymorphisms (SNP) have been identified in the protein, apolipoprotein L1 (apoL1) which is just one member of a family of six conserved proteins. You will perform computer analysis to identify SNPs in apoL1.
Is there a possibility into providing me with a guidance into reaching for the answer please that will be appreciated

can I be specific in this and do a computer analysis of APOL1 and single nucleotide polymorphisms in chronic kidney disease (CDK). Will I be using OMIM and Dsnp for this one, any guidance please, that will be really helpful.

Hello!

What sort of data are you working with? If you have VCF files, the task is as easy as figuring out the genomic coordinates of apoL1 and then taking out the variants in the VCF file that occur within the exons of apoL1. You can find genomic coordinates by e.g. using the UCSC Genome Browser (just google it).

Good luck!