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GATK SNP multi-sample without known SNP database ?
I am working on identifying the SNPs in the genome of an insect which is sequenced in three samples. Following the GATK best practice pipeline i have...
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Prior probability during SNP calling
Most SNP caller, such as HaplotypeCaller apply Bayes method to call SNP. HaplotypeCaller use 1KG / dbsnp data set as prior probability.
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Identifying a good SNP on IGV
I start working with IGV, but I have some doubts in how to identify a good SPN in this program. First I download the new Soybean Genome on Phytozome (Gmax_275_v2.0.fa...
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SNVer error on pooled sample
Hi there,
I'm running SNVer 0.2.0 on Mac OS x 10.6.8.
The input is a bam file generated from Ion Torrent data - Torrent...
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Samtools mpileup/bcftools
Hi all,
I read through samtools manuals several times, but I'm still not clear on how exactly samtools & bcftools decide to call a SNP. I've...