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Complete Genomics
DNA single-strand circularization followed by rolling circle amplification (RCA) to form DNA nanoballs for DNBSEQ.
Topics: 52
Posts: 165
Last Post:
G400 fastq header description?
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52 | 165 |
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Element Biosciences
Avidity sequencing - multivalent nucleotide ligands on dye-labeled cores to form polymerase-polymer nucleotide complexes bound to clonal copies of DNA targets.
Topics: 2
Posts: 5
Last Post:
Weird 16S custom primer issue on Aviti runs
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2 | 5 |
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Illumina (Solexa)
Bridged amplification & clustering followed by sequencing by synthesis.
Topics: 3,069
Posts: 16,772
Last Post:
weird Q30 drop in the recent nextseq run
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3,069 | 16,772 |
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Ion Torrent
Integrated electronic detection of protons released upon base incorporation. (Thermo Fisher Scientific)
Topics: 388
Posts: 2,175
Last Post:
Proton Data
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388 | 2,175 |
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Oxford Nanopore
Single-molecule sequencing via a protein nanopore.
Topics: 126
Posts: 612
Last Post:
Size of the output promethION v. minION
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126 | 612 |
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Pacific Biosciences
Single-molecule real-time observation of DNA polymerase using zero-mode waveguide (ZMW) optical confinement nanostructures or sequencing by binding (SBB)
Topics: 390
Posts: 2,183
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390 | 2,183 |
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Singular Genomics
Optical ensemble sequencing by synthesis via fluorescently labeled reversible terminated nucleotides.
Topics: 0
Posts: 0
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0 | 0 |
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Ultima Genomics
Open flow cell design on a circular wafer and mostly natural nucleotides that allow optical end-point detection without reversible terminators.
Topics: 0
Posts: 0
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0 | 0 |
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Sanger/Dye Terminator
Automated dye terminator ("Sanger") chemistries
Topics: 78
Posts: 288
Last Post:
Improving Sequencing Results
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78 | 288 |
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Service Providers
Discussions about next gen sequencing service providers, reviews & experiences, etc. No overtly commercial content permitted without prior approval.
Topics: 75
Posts: 477
Last Post:
GMP whole genome sequencing prices
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75 | 477 |
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Archived Forums
A place for discussion of older forums and sequencing technologies.
Topics: 1,361
Posts: 7,278
Last Post:
Rapid Libraries
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1,361 | 7,278 |
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Sub-Forums:
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Next-generation sequencing (NGS) is changing how clinical and public health laboratories detect pathogens, track antimicrobial resistance,...10-01-2026, 05:37 AM -
Much of the genetic basis of Alzheimer's disease and related dementias (AD/ADRD) is still unexplained, and some of the answers may sit...10-01-2026, 05:06 AM
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM -
Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.
We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing... -
The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
This convergence of genetics, immunology, and computation...09-01-2026, 05:41 AM