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SNP and indel calling in Bisulfite data
I am working on a bisulfite-treated sequence and I am interested in the SNP, indels, and methylated sites. I have used Bismark and bowtie2 to map the...
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Variation calling, pool samples or not?
I seem to remember from talks and manuals that it's good practice to pool reads from all available samples when calling (per-sample) variations, as the...