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  • Somatic mutations in dbsnp--constant 5%

    The number of Somatic mutations in each cancer type or in each person may range a lot, but the number in dbsnp is comparative. Exome sequencing almsot <10 and Whole genome sequencing 50<x<200. I think this is very interesting, that there are some potential common mechanisms in cancer. But I don’t have enough power to research it. Is there anyone can give me some suggestions?

    sorry for making a mistake
    Last edited by LiLin; 05-16-2013, 02:13 AM.

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  • seqadmin
    Genetic Variation in Immunogenetics and Antibody Diversity
    by seqadmin



    The field of immunogenetics explores how genetic variations influence immune responses and susceptibility to disease. In a recent SEQanswers webinar, Oscar Rodriguez, Ph.D., Postdoctoral Researcher at the University of Louisville, and Ruben Martínez Barricarte, Ph.D., Assistant Professor of Medicine at Vanderbilt University, shared recent advancements in immunogenetics. This article discusses their research on genetic variation in antibody loci, antibody production processes,...
    11-06-2024, 07:24 PM
  • seqadmin
    Choosing Between NGS and qPCR
    by seqadmin



    Next-generation sequencing (NGS) and quantitative polymerase chain reaction (qPCR) are essential techniques for investigating the genome, transcriptome, and epigenome. In many cases, choosing the appropriate technique is straightforward, but in others, it can be more challenging to determine the most effective option. A simple distinction is that smaller, more focused projects are typically better suited for qPCR, while larger, more complex datasets benefit from NGS. However,...
    10-18-2024, 07:11 AM

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