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Genetic Analysis of New Strains of West Nile Virus
Researchers from the University of Connecticut (UConn) have successfully determined the complete protein-coding sequences of West Nile virus strains found...
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BabySeq Project Reveals Treatable Genetic Variants
Researchers from Mass General Brigham and Boston Children's Hospital have reported significant findings from the ongoing BabySeq Project, the world's...
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Single-Cell Sequencing Data Analysis
Register now for our webinar to learn all about single-cell sequencing data analysis. We'll cover the important steps of the analysis...
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seqadmin started a topic Genetic Discoveries Transform Our Understanding of Primate Diversity and Behaviorin NewsGenetic Discoveries Transform Our Understanding of Primate Diversity and Behavior
In the face of pressing threats such as climate change, habitat loss, and illegal trading and hunting, understanding primate genetic diversity has become...
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seqadmin started a topic Deep Sequencing Unearths Novel Genetic Variants: Enhancing Precision Medicine for Vascular Anomaliesin NewsDeep Sequencing Unearths Novel Genetic Variants: Enhancing Precision Medicine for Vascular Anomalies
A breakthrough study conducted by researchers at Children’s Hospital of Philadelphia (CHOP) has revealed that comprehensive "deep sequencing"...
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A Review of Next-Generation Sequencing Methods for Studying Epigenetics—Part 1
- Published: 05-31-2023, 01:07 PM
- 322 views
- 0 comments
in ArticlesA Review of Next-Generation Sequencing Methods for Studying Epigenetics—Part 1
Developments in sequencing technologies and methodologies have transformed the field of epigenetics, giving researchers a better way to understand the complex world of gene regulation and heritable modifications. This article explores some of the diverse sequencing methods employed in the study of epigenetics, ranging from classic techniques to cutting-edge innovations while providing a brief overview of their processes, applications, and advances.
Methylation Detect... -
seqadmin started a topic Unveiling Genetic Associations Through Transcription Factor Binding Quantitative Trait Lociin NewsUnveiling Genetic Associations Through Transcription Factor Binding Quantitative Trait Loci
Genome-wide association studies (GWAS) have revolutionized our understanding of genetic associations with complex traits and diseases, but interpreting...
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Exploring Bioinformatics for Whole Genome Sequencing (WGS) Data
Join us for an insightful webinar, where we will dive into the bioinformatics process so you can learn how to analyze whole genome sequencing data. Our...
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seqadmin started a topic Exploring French-Canadian Ancestry: Insights into Migration, Settlement Patterns, and Genetic Structurein NewsExploring French-Canadian Ancestry: Insights into Migration, Settlement Patterns, and Genetic Structure
An exciting new study combines comprehensive genealogical records and genotype data, offering unique insights into the complex history and genetic structure...
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Largest Catalog of Human Protein-Coding Variation Unveiled
RGC-ME Dataset Offers Valuable Resource for Precision Medicine Efforts
In a groundbreaking development, researchers have unveiled the largest...
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Differential Expression and Data Visualization: Recommended Tools for Next-Level Sequencing Analysis
- Published: 05-23-2023, 01:59 PM
- 327 views
- 0 comments
in ArticlesDifferential Expression and Data Visualization: Recommended Tools for Next-Level Sequencing Analysis
After covering QC and alignment tools in the first segment and variant analysis and genome assembly in the second segment, we’re wrapping up with a discussion about tools for differential gene expression analysis and data visualization. In this article, we include recommendations from the following experts: Dr. Mark Ziemann, Senior Lecturer in Biotechnology and Bioinformatics, Deakin University; Dr. Medhat Mahmoud Postdoctoral Research Fellow at Baylor College of Medicine;... -
seqadmin started a topic Introducing ProtVar: A Web Tool for Contextualizing and Interpreting Human Missense Variation in Proteinsin NewsIntroducing ProtVar: A Web Tool for Contextualizing and Interpreting Human Missense Variation in Proteins
On May 24, EMBL's European Bioinformatics Institute (EMBL-EBI) will unveil ProtVar, an innovative web tool designed to assist users in comprehending and...
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Hello ArthurD and welcome to the community. What types of sequencing or analysis are you performing in your lab?...
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Variant Analysis and Genome Assembly: Recommended Tools for Next-Level Sequencing Analysis
- Published: 05-19-2023, 10:10 AM
- 724 views
- 0 comments
in ArticlesVariant Analysis and Genome Assembly: Recommended Tools for Next-Level Sequencing Analysis
Continuing from our previous article, we share variant analysis and genome assembly tools recommended by our experts Dr. Medhat Mahmoud, Postdoctoral Research Fellow at Baylor College of Medicine, and Dr. Ming "Tommy" Tang, Director of Computational Biology at Immunitas and author of From Cell Line to Command Line.
Variant detection and analysis tools
Mahmoud classifies variant detection work into two main groups: short variants (<50... -
SEQanswers June Challenge: Share Your Knowledge and Win
We're excited to announce a new competition for the month of June! We're giving away a $50 Amazon gift card to the member who answers the most questions...
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AMP Releases Recommendations for NGS Germline Variant Confirmation
Next-generation sequencing (NGS) has truly revolutionized clinical molecular genetic testing, becoming the primary method in this field. However, there...
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Decoding Animal Evolution: Insights from Chromosome-Scale Genomes
For over a century, biologists have been fascinated by the origins of the earliest animals that emerged in the ancient oceans more than half a billion...
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QC, Alignment, and Mapping: Recommended Tools for Next-Level Sequencing Analysis
- Published: 05-16-2023, 10:17 AM
- 663 views
- 0 comments
in ArticlesQC, Alignment, and Mapping: Recommended Tools for Next-Level Sequencing Analysis
With new tools and computational resources being released regularly, it can be hard to determine which are best suited for the analysis process and which older tools continue to be maintained. In an effort to assist the sequencing community, we interviewed three highly skilled bioinformaticians about their recommended tools for several important analysis applications.
Quality control and preprocessing tools
“Garbage in, garbage out” is a popular... -
Exploring the Role of Promoter Dominance and RNA Diversity
In the intricate realm of cellular biology, the identity and function of individual cells and tissues transcend the uniformity of DNA sequences shared...
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New Technique Enables Single-Cell RNA Sequencing in FFPE Tissues
Researchers have developed a groundbreaking method for performing single cell/nucleus RNA sequencing (sc/snRNA-seq) on formalin-fixed paraffin-embedded...
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