Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • bwa for mate pair reads

    Has anyone used BWA for mate pair reads? We've had some trouble on first effort. Appears it's mapping the inward facing reads but not handling the outward facing reads (the true jumps). Any advice? Is it necessary to invert reads first?

  • #2
    BWA does not support jumping libraries. Nonetheless, you may consider to switch read1 and read2 (putting read2 as the first file and read1 as the second). I have not tried though.

    EDIT: I was right. Forget my claim. BWA does not support jumping libraries. Please use another aligner.
    Last edited by lh3; 03-30-2010, 05:30 AM.

    Comment

    Latest Articles

    Collapse

    • seqadmin
      Latest Developments in Precision Medicine
      by seqadmin



      Technological advances have led to drastic improvements in the field of precision medicine, enabling more personalized approaches to treatment. This article explores four leading groups that are overcoming many of the challenges of genomic profiling and precision medicine through their innovative platforms and technologies.

      Somatic Genomics
      “We have such a tremendous amount of genetic diversity that exists within each of us, and not just between us as individuals,”...
      Today, 01:16 PM
    • seqadmin
      Recent Advances in Sequencing Analysis Tools
      by seqadmin


      The sequencing world is rapidly changing due to declining costs, enhanced accuracies, and the advent of newer, cutting-edge instruments. Equally important to these developments are improvements in sequencing analysis, a process that converts vast amounts of raw data into a comprehensible and meaningful form. This complex task requires expertise and the right analysis tools. In this article, we highlight the progress and innovation in sequencing analysis by reviewing several of the...
      05-06-2024, 07:48 AM

    ad_right_rmr

    Collapse

    News

    Collapse

    Topics Statistics Last Post
    Started by seqadmin, Today, 07:15 AM
    0 responses
    10 views
    0 likes
    Last Post seqadmin  
    Started by seqadmin, Yesterday, 10:28 AM
    0 responses
    15 views
    0 likes
    Last Post seqadmin  
    Started by seqadmin, Yesterday, 07:35 AM
    0 responses
    16 views
    0 likes
    Last Post seqadmin  
    Started by seqadmin, 05-22-2024, 02:06 PM
    0 responses
    8 views
    0 likes
    Last Post seqadmin  
    Working...
    X