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  • plattsa
    Member
    • Mar 2009
    • 17

    #1

    C value estimates from NGS data?

    All,

    We're doing some genome assembly work in plants where ploidy and chromosome counts seem to change from one corner of a field to another. We have some expected c-values from the lit (eg Lysak et al, Johnson etc), but whether these still are useful for our plants we're not entirely sure.

    Can anyone point to a technique for estimating C-values from variables such as the total k-mer count, expected read error rate and k-mer depth distributions? It seems like something such as this might be possible...?

    Thanks for any ideas.

    AP

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