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Exeter-Led Study Maps What an Average Human Genome Looks Like
A new study from the University of Exeter has characterized what counts as an “average” human genome, offering a reference point for normal genetic... -
SEQadmin2 started a topic Long-Read Sequencing Uncovers Cancer Mutations Conventional Testing Missedin NewsLong-Read Sequencing Uncovers Cancer Mutations Conventional Testing Missed
The University of Michigan’s Oncology Sequencing Program, known as MiOncoSeq, analyzes DNA and RNA from patients’ tumors and healthy tissue to find... -
Mayo Clinic-Led Study Detects DNA Mutations Across Noncancerous Tissues
A Mayo Clinic-led study has shown how to detect a broad range of DNA mutations in noncancerous human tissues and across the genome. The analysis, drawing... -
Study Finds Chromatin Motion Holds Steady Until Cells Face Stress
Living human cells appear to hold the local movement of their DNA at a remarkably steady level through most of the cell cycle, only dialing it up when... -
Larger Datasets Reveal Additional Switches That Control Gene Expression
Most GWAS loci fall in regions that control gene expression rather than in the genes themselves, and linking those variants to eQTL and sQTL signals has... -
Computational Tool Captures How Chromatin Folds at Scale
Studying how chromatin changes requires capturing molecular movements and interactions that are difficult to resolve experimentally. Now, an international... -
SEQadmin2 started a topic Spatial Transcriptomics and Metabolite Mapping Combined on a Single Tissue Slidein NewsSpatial Transcriptomics and Metabolite Mapping Combined on a Single Tissue Slide
Spatial transcriptomics (ST) shows which genes are active and where within a tissue, while spatial metabolomics (SM) maps the location of metabolites,... -
Bat1K Consortium Combines Genomes and Fossils to Trace Bat Origins
An international consortium has sequenced and compared 103 bat genomes spanning all 21 recognized bat families, then combined that genomic dataset with...