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SEQadmin2 started a topic Giant Sunflower Genomes Advance the Case for Climate-Resilient Perennial Cropsin NewsGiant Sunflower Genomes Advance the Case for Climate-Resilient Perennial Crops
Researchers at the Land Institute and the HudsonAlpha Institute for Biotechnology have produced the first chromosome-scale, haplotype-phased genome assemblies...
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New Tool Estimates Cellular Age from Gene Activity Patterns
Aging is a major risk factor for many diseases, but reliable methods for measuring how quickly cells age have been lacking. Now, researchers at Karolinska...
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DNA Repair Enzymes Favor Specific Genome Sequences, Study Finds
An unhealed wound leaves a scar. In the genome, an unrepaired DNA lesion leaves a mutation — a permanent edit to the genetic code. Mutations can disrupt...Last edited by SEQadmin2; 08-13-2026, 12:31 PM.
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Single-Cell Atlas Pinpoints Spinal Neurons Controlling Movement Speed
Scientists at St. Jude Children’s Research Hospital have built a single-cell atlas of V1 interneurons, a key class of spinal neurons involved in motor...
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Consortium Completes First Full Diploid Human Genome
Scientists have reconstructed the complete genome of a real person, including full sets of chromosomes from each parent, an achievement expected to advance...
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Long-Read Sequencing Closes Decades-Old Gaps in the Medaka Genome
Scientists have completed a long-standing effort to fully sequence the genome of the medaka, or Japanese rice fish, a widely used model organism in biological...
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Beyond CRISPR/Cas9: Understand, Choose, and Use the Right Genome Editing Tool
- Published: 08-03-2026, 06:54 AM
- 110 views
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in ArticlesBeyond CRISPR/Cas9: Understand, Choose, and Use the Right Genome Editing Tool
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...Last edited by SEQadmin2; 08-03-2026, 10:43 AM. -
Genomic Surveillance as a Public Health Measure
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...
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New Genomic Method Uncovers Ancient Hominin DNA
UC Berkeley researchers have developed a new computational technique that identifies regions of the human genome inherited from previously unknown archaic...
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