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  • Pacific Biosciences: Spotlight on the Companies Shaping Genetic Research

    • Published: 07-10-2023, 07:14 AM
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    Pacific Biosciences: Spotlight on the Companies Shaping Genetic Research



    Established in 2004, Pacific Biosciences (PacBio) set out to create innovative tools that would elevate our understanding of genomics. Over the years, they have grown into global leaders in the field, known for their revolutionary HiFi sequencing—a high-accuracy, long-read sequencing solution.

    Their journey began with the PacBio RS, their first commercial release, which employed their Single Molecule, Real-Time (SMRT) sequencing technology. This marked the beginning...
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  • Onso from Pacific Biosciences: Latest Sequencing Technologies—Part 4

    • Published: 12-22-2022, 01:20 PM
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    Onso from Pacific Biosciences: Latest Sequencing Technologies—Part 4

    Onso was the second sequencer Pacific Biosciences (PacBio) revealed during this year’s American Society of Human Genetics meeting (read about the first sequencer here). This benchtop sequencer uses sequencing by binding (SBB), a method unlike any other instrument on the market. SBB incorporates native nucleotides, has reduced molecular scarring, and reportedly results in significantly higher accuracy base calls than traditional short-read sequencers. The following sections highlight the important...
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