AVITI from Element Biosciences: Latest Sequencing Technologies—Part 6
Element Biosciences made its sequencing market debut this year when it released AVITI, its first sequencer. The AVITI System uses avidity sequencing, a novel sequencing chemistry that delivers higher quality data, decreases cycle times, and requires lower reagent concentrations. This new instrument reportedly features lower operating and start-up costs while maintaining quality sequencing.
Read type and length
AVITI is a short-read benchtop sequencer that also offers an innovative...
DNBSEQ-G400 from Complete Genomics: Latest Sequencing Technologies—Part 5
Complete Genomics (an MGI company) released the DNBSEQ-G400 into the U.S. market this summer. DNBSEQ-G400 is a benchtop sequencer that uses MGI’S DNA Nanoball sequencing technology (DNBSEQ) that boasts low index hopping, low amplification bias, and low PCR amplification error accumulation. In addition, the instrument is capable of using an improved antibody-based chemistry, CoolMPS sequencing reagent, that reduces errors and improves the sequencing quality.
Onso from Pacific Biosciences: Latest Sequencing Technologies—Part 4
Onso was the second sequencer Pacific Biosciences (PacBio) revealed during this year’s American Society of Human Genetics meeting (read about the first sequencer here). This benchtop sequencer uses sequencing by binding (SBB), a method unlike any other instrument on the market. SBB incorporates native nucleotides, has reduced molecular scarring, and reportedly results in significantly higher accuracy base calls than traditional short-read sequencers. The following sections highlight the important...