Hi!
We are investigating the effect of TF-mediated mutations on genome. In the validation part, we narrowed our regions to 1. We sequenced...
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Amplicon based sequencing Mutation Calling
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Cosmic database analysis
Hello everyone!
Im trying to estimate mutation frequences in cancer using cosmic database. But how can i download the total samples (list... -
biased mutation calling/false negatives from HALOPLEX datasets?
Hi everyone,
I'm wondering if someone has an opinion/experience with that. Using Haloplex, considering the frequent occurence of restriction... -
Mutation Frequency vs. Depth of Coverage
Tumors are composed of malignant cells, stromal cells and immune cells. Accordingly, a tumor with a heterozygous mutation may only have 40% cancer cellularity...
