The Human Genome Project generated the human reference genome over 13 years at a cost of $3 billion.1 That massive undertaking used the low-throughput Sanger method, which sequences one DNA fragment at a time. While this strategy remains useful for interrogating small genomic regions, modern next-generation sequencing (NGS) technologies can simultaneously sequence millions of fragments in a single run, enabling the analysis of hundreds to thousands of genes at once.
Today, rapid...
