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  • Pacific Biosciences: Spotlight on the Companies Shaping Genetic Research



    Established in 2004, Pacific Biosciences (PacBio) set out to create innovative tools that would elevate our understanding of genomics. Over the years, they have grown into global leaders in the field, known for their revolutionary HiFi sequencing—a high-accuracy, long-read sequencing solution.

    Their journey began with the PacBio RS, their first commercial release, which employed their Single Molecule, Real-Time (SMRT) sequencing technology. This marked the beginning...
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  • AVITI from Element Biosciences: Latest Sequencing Technologies—Part 6

    Element Biosciences made its sequencing market debut this year when it released AVITI, its first sequencer. The AVITI System uses avidity sequencing, a novel sequencing chemistry that delivers higher quality data, decreases cycle times, and requires lower reagent concentrations. This new instrument reportedly features lower operating and start-up costs while maintaining quality sequencing.

    Read type and length
    AVITI is a short-read benchtop sequencer that also offers an innovative...
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  • DNBSEQ-G400 from Complete Genomics: Latest Sequencing Technologies—Part 5

    Complete Genomics (an MGI company) released the DNBSEQ-G400 into the U.S. market this summer. DNBSEQ-G400 is a benchtop sequencer that uses MGI’S DNA Nanoball sequencing technology (DNBSEQ) that boasts low index hopping, low amplification bias, and low PCR amplification error accumulation. In addition, the instrument is capable of using an improved antibody-based chemistry, CoolMPS sequencing reagent, that reduces errors and improves the sequencing quality.

    Read type and length...
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  • Onso from Pacific Biosciences: Latest Sequencing Technologies—Part 4

    Onso was the second sequencer Pacific Biosciences (PacBio) revealed during this year’s American Society of Human Genetics meeting (read about the first sequencer here). This benchtop sequencer uses sequencing by binding (SBB), a method unlike any other instrument on the market. SBB incorporates native nucleotides, has reduced molecular scarring, and reportedly results in significantly higher accuracy base calls than traditional short-read sequencers. The following sections highlight the important...
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  • Revio from Pacific Biosciences: Latest Sequencing Technologies—Part 3

    Pacific Biosciences (PacBio) revealed two new sequencers during this year’s American Society of Human Genetics meeting. The first instrument, Revio, which will be covered in this article, is a significant upgrade from their previous Sequel II device. It has lower costs, shorter run times, more SMRT Cells and zero-mode waveguides (ZMW), and significantly higher output compared to PacBio’s other sequencers.

    Read type and length
    As a part of PacBio’s long-read sequencing systems,...
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  • Refurbished Hiseq 4000 & Hiseq 2500v4 in-stock

    Greetings,

    We have the following two systems in-stock. Please message me if you are interested.

    Like-new Illumina HiSeq...
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  • sgequip
    started a topic For Sale SOLiD

    For Sale SOLiD

    For Sale:

    (1) ABI 5500xl SOLiD sequencer

    (1) Applied Biosystems SOLiD 4 Analyzer

    (1) Applied Biosystems...
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  • Is there any empirical estimate of idle sequencer capacity available?

    At my local university I have heard rumors that there "is a high percentage of idle sequencer capacity worldwide." Unfortunately I was not able...
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  • Rumor: new Illumina sequencing instrument?

    I've heard rumors of a new Illumina sequencing instrument (not talking about the HiSeq 2500 upgrades). Anyone else heard anything?
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  • 454 GS Junior for sale (complete system)

    Complete 454 GS Junior NGS Sequencing System for sale

    Great benchtop next-gen sequencer for Amplicon Sequencing or Whole Genome Sequencing...
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