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Transcription factor colocalization p-values
I have ChIPSeq peak data for TF A and TF B in bed format. On examining these in a genome browser together, I see that there are many instances when TFBS...
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Transcription factors and closed/activated/repressed chromatin
Is it possible for a TF to bind to closed chromatin without opening it? I mean, is it possible for chip-seq peaks of non-pioneer TFs to exist in closed...
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Find binding sites for transcription factor in a sequence
I want to look at the promoter sequence of human IgM (ENSG00000162897), which I can easily retrieve with biomart. I'm specifically looking for potential...
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Advice on starting a new RNA-protein interaction project
I have been using Tandem-affinity purification (TAP) to identify transcription factor binding proteins. I am interested in trying to apply this approach...