CNVnator make histogram problem

CNVboy

Member

Join Date: Jun 2011
Posts: 27

CNVnator make histogram problem

07-07-2011, 12:15 PM

I'm doing trio data analysis; so I merged those small root files into larger ones chromosome by chromosome. The merge process looks ok.

But when I tried to make histogram out of it, I got errors as below:

Code:

Calculating histogram with bin size of 100 for chromosome 'chr3' ...
Making directory bin_100 ...
Making GC histogram for 'chr3' ...
SysError in <TFile::Seek>: cannot seek to position -1646234942 in file NA12878_3.root, retpos=-1 (Invalid argument)
Error in <TFile::ReadBuffer>: error reading all requested bytes from file NA12878_3.root, got 0 of 1915944962
Error in <TKey::ReadFile>: Failed to read data.

What's the problem here?

thanks

Tags: None

Previous template Next

Multiomic Liquid Biopsy: What DNA/RNA Panels Reveal That DNA Alone Can’t

by SEQadmin2

Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?

Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...
- Channel: Articles
10-14-2026, 09:55 AM
New Genomics Technologies Take Aim at Long-Standing Limits

by SEQadmin2

Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.

We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing...
- Channel: Articles
09-28-2026, 10:25 AM

Topics	Statistics	Last Post
Exeter-Led Study Maps What an Average Human Genome Looks Like by SEQadmin2 Started by SEQadmin2, 10-22-2026, 11:13 AM	0 responses 30 views 0 reactions	Last Post by SEQadmin2 10-22-2026, 11:13 AM
Long-Read Sequencing Uncovers Cancer Mutations Conventional Testing Missed by SEQadmin2 Started by SEQadmin2, 10-22-2026, 10:48 AM	0 responses 22 views 0 reactions	Last Post by SEQadmin2 10-22-2026, 10:48 AM
Mayo Clinic-Led Study Detects DNA Mutations Across Noncancerous Tissues by SEQadmin2 Started by SEQadmin2, 10-15-2026, 10:52 AM	0 responses 39 views 0 reactions	Last Post by SEQadmin2 10-15-2026, 10:52 AM
Study Finds Chromatin Motion Holds Steady Until Cells Face Stress by SEQadmin2 Started by SEQadmin2, 10-14-2026, 05:39 AM	0 responses 45 views 0 reactions	Last Post by SEQadmin2 10-14-2026, 05:39 AM

Unconfigured Ad

CNVnator make histogram problem

Latest Articles

ad_right_rmr

News