I would like to phase whole-genome datasets, some of which are single-end read datasets and some of which are paired-end datasets. Does anyone have experience with this? Should I simply generate a list of SNPs and feed it to existing phasing algorithms? Is there software that can take the raw read data into account (IE SNPs that appear on the same read)?
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
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04-22-2024, 07:01 AM -
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