Hi all-
I'm swaying from my norm and posting a non-de novo question (ekk!). Does anybody have experience with zoom as a read-mapper? It seems to be able to map illumina reads that have been stitched together from each side of a clone, but possibly only with 2 mismatches, something highly unlikely even with the latest processing pipeline.
cheers,
-mark
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The complexity of cancer is clearly demonstrated in the diverse ecosystem of the tumor microenvironment (TME). The TME is made up of numerous cell types and its development begins with the changes that happen during oncogenesis. “Genomic mutations, copy number changes, epigenetic alterations, and alternative gene expression occur to varying degrees within the affected tumor cells,” explained Andrea O’Hara, Ph.D., Strategic Technical Specialist at Azenta. “As...-
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