Hello everyone,
We use annovar for annotation. In the output is also a PhyloP score. All values in our output are between 0 and 1. Is it correct, that that value is the P-value for conservation? So is the SNP is more conserved, if the value is closer to 0? Is it significant conserved < 0.05?
Up to now I thought, that the position is first conserved for a PhyloP score > 3 and that it is also possible that the value is < 0. So I am a little bit confused about the annovar PhyloP score. Who can help?
Best regards
Robby
We use annovar for annotation. In the output is also a PhyloP score. All values in our output are between 0 and 1. Is it correct, that that value is the P-value for conservation? So is the SNP is more conserved, if the value is closer to 0? Is it significant conserved < 0.05?
Up to now I thought, that the position is first conserved for a PhyloP score > 3 and that it is also possible that the value is < 0. So I am a little bit confused about the annovar PhyloP score. Who can help?
Best regards
Robby
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