Hi friends,
I'm working with some reads' simulations from Illumina paired end data and I try to find the link between the coverage depth and unique k-mer.
My hypothesis : with a HIGH coverage depth we must have LESS unique k-mer. Most of nucleotides are covered.
However I see for a 20 mers the complete opposite result :for a high coverage depth I have got a high uniqueness ratio whereas my hypothesis is validated for a 80 mers.
Actually I look for a paper about it but can not find it.
Have you got any idea about my hypothesis or these results ?
advance thanks,
I'm working with some reads' simulations from Illumina paired end data and I try to find the link between the coverage depth and unique k-mer.
My hypothesis : with a HIGH coverage depth we must have LESS unique k-mer. Most of nucleotides are covered.
However I see for a 20 mers the complete opposite result :for a high coverage depth I have got a high uniqueness ratio whereas my hypothesis is validated for a 80 mers.
Actually I look for a paper about it but can not find it.
Have you got any idea about my hypothesis or these results ?
advance thanks,
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