Hello,
I was trying to use fastq-dump to convert a .sra file to .fastq format.
The data contains paired end reads, so when I type in commands,
fastq-dump --split-files .sra, it gives two files, *_1.fastq and *_2.fastq.
But the problem is the size of the two files are different, one is a lot bigger than the other. This doesn't seems to be right.
Does anyone know why this happens? and how to fix it? Shouldn't the two files contain the same number of reads, so that the size should be the same as well?
Thank you,
Hui
I was trying to use fastq-dump to convert a .sra file to .fastq format.
The data contains paired end reads, so when I type in commands,
fastq-dump --split-files .sra, it gives two files, *_1.fastq and *_2.fastq.
But the problem is the size of the two files are different, one is a lot bigger than the other. This doesn't seems to be right.
Does anyone know why this happens? and how to fix it? Shouldn't the two files contain the same number of reads, so that the size should be the same as well?
Thank you,
Hui
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