I have a kind of basic question- I have a SE chipseq data for histone modification, Do we need to a specific wet lab experiment before we run NPS alogrithm for checking nucleosome positioning. The data I have is from regular chipseq and is not specifically from nucleosome fraction. My idea is to overlay the histone modification regions with nucleosome positioning. Any suggestion or feedback please.
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Like all molecular biology applications, next-generation sequencing (NGS) workflows require diligent quality control (QC) measures to ensure accurate and reproducible results. Proper QC begins at nucleic acid extraction and continues all the way through to data analysis. This article outlines the key QC steps in an NGS workflow, along with the commonly used tools and techniques.
Nucleic Acid Quality Control
Preparing for NGS starts with isolating the...-
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In recent years, precision medicine has become a major focus for researchers and healthcare professionals. This approach offers personalized treatment and wellness plans by utilizing insights from each person's unique biology and lifestyle to deliver more effective care. Its advancement relies on innovative technologies that enable a deeper understanding of individual variability. In a joint documentary with our colleagues at Biocompare, we examined the foundational principles of precision...-
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